nitrosurea

Example:While nitrosourea damages DNA directly, another class of drugs like antimetabolites interfere with DNA synthesis indirectly.

Definition:A chemical used in cancer chemotherapy that interferes with the normal functioning of enzymes necessary for nucleic acid metabolism, slowing cell division but not by damaging DNA.

Example:Unlike nitrosoureas, which are cytotoxic, some cytostatic agents like vinblastine do not directly damage DNA.

Definition:An agent that inhibits or slows down cell division but does not necessarily damage the DNA directly, such as antimetabolites, plant extracts, and other natural substances.