bioisostere
noun as in strong fondness
Word Combinations
Example:Researchers used a bioisosteric transformation to enhance the oral bioavailability of a drug without significantly altering its potency.
Definition:The substitution of one bioisostere for another in a chemical molecule to optimize its properties while maintaining biological activity.
From bioisosteric transformation
Example:The bioisosteric replacement of a hydroxyl group with a piperazine group in the drug molecule improved its lipophilicity and aqueous solubility.
Definition:The process of replacing a specific functional group in a molecule with a bioisostere to improve certain drug properties such as solubility or metabolic stability.
From bioisosteric replacement
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